Publications

  • An in vitro model that recapitulates the epithelial to mesenchymal transition (EMT) in human breast cancer

    Katz E, Dubois-Marshall S, Sims AH, Gautier P, Meehan RR and Harrison DJ

    PLOS One 2011 (in press)

  • A gene on the HER2 amplicon C35 is an oncogene in breast cancer whose actions are prevented by inhibition of Syk

    Katz E,Dubois-Marshall S, Simms AH, Faratian D, Li J, Smith ES, Quinn JA, Edward M, Meehan RR, Evans EE, Langdon SP, Harrison DJ,

    Br J Cancer 2010 Jul 27 103 (3) 401-10 epub 2010 Jul 13 PubMed PMID 20628393; PubMed Central PMCID: PMC2920017

  • Analysis of active and inactive X chromosome architecture reveals the independent organisation of 30mm and large scale chromatin structures

    Naughton C, Sproul D, Hamilton C, Gilbert N

    Mol Cell 2010 Nov 12 40(3) 397:409 Pub Med PMID 21070966

  • Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methlcytosine and 5-hydroxymethycytosine in DNA

    Nestor C, Ruzov A, Meehan R, Dunican D,

    Biotechnieques 2010 Apr 48(4) 317:9 PubMed PMID: 20569209

  • Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise

    Whitelaw NC,Chong S, Morgan DK, Nestor C, Bruxner TJ, Ashe A, Lambley E, Meehan R, Whitelaw E

    Genome Biol 2010 Nov 19 ; 11 (11) R111 PubMed PMID: 21092094

  • Ring1B compacts chromotin structure and represses gene expression independent of histone ubiquitination

    Eskeland R, Leeb M, Grimes GR, Kress C, Boyle S, Sproul D, Gilbert N, Fan Y, Skoultchi AI, Wutz A, Bickmore W

    Mol Cell 2010 May 14; 38(3): 452-64 Pub Med PMID: 20471950

  • MBD4 and MLH1 are required for apoptotic inductino in xDNMT1 depeleted embryos development

    Ruzov A, Shorning B, Mortuse wicz O, Dunican DS, Leonhardt H, Meehan RR

    2009 Jul 136 2277-86 PubMed PMID : 19502488: pubMed Central PMCID: PMC2729342

  • The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways

    Ruzov A, Hackett JA, Prokhortchouk A, Reddington JP, Madej MJ, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR

    2009 Mar 136(5) 723-7 Epub 2009 Jan 21 PubMed PMID: 19158184 PubMed Central PMCID: PMC2685940

  • The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways.

    Authors: Ruzov A, Hackett JA, Prokhortchouk A, Reddington JP, Madej MJ, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR.

    Development. 2009 Mar 136(5):723-7.

  • The non-methylated DNA-binding function o fKaiso is not required in early Xenopus laevis development

    Ruzov A, Savitskaya E, Hackett JA, Reddington JP, Prokhortchouk A, Madej MJ, Chekanov N, Li M, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR

    2009 Mar 136(5) 729-38 Epub 2009 Jan 21 Pub Med PMID: 19158185 PubMed Central PMCID PMC2685941

  • The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development.

    Authors: Ruzov A, Savitskaya E, Hackett JA, Reddington JP, Prokhortchouk A, Madej MJ, Chekanov N, Li M, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR.

    Development. 2009 Mar 136(5):729-38.

  • xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embroyos independently of its catalytic function

    Dunican DS, Ruzov A, Hackett JA, Meehan RR

    Development 2008 Apr 135(7): 1295-302 Epub 2008 Feb 27 PubMed PMID: 1835009

  • xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function. Development.

    Authors: Dunican DS, Ruzov A, Hackett JA, Meehan RR.

    2008 Apr;135(7):1295-302. Epub 2008 Feb 27.

  • Epigenetic silencing in embryogenesis.

    Authors: Meehan RR, Dunican DS, Ruzov A, Pennings S.

    Exp Cell Res. 2005 Oct 1;309(2):241-9.

  • A determining influence for CpG dinucleotides on nucleosome positioning in vitro.

    Authors: Davey CS, Pennings S, Reilly C, Meehan RR, Allan J.

    Nucleic Acids Res. 2004 Aug 13;32(14):4322-31. Print 2004.

  • Kaiso is a genome-wide repressor of transcription that is essential for amphibian development. Development.

    Authors: Ruzov A, Dunican DS, Prokhortchouk A, Pennings S, Stancheva I, Prokhortchouk E, Meehan RR

    2004 Dec;131(24):6185-94. Epub 2004 Nov 17.

  • The effect of interspecific oocytes on demethylation of sperm DNA

    Beaujean N, Taylor JE, McGarry M, Gardner JO, Wilmut I, Loi P, Ptak G, Galli C, Lazzari G, Bird A, Young LE, Meehan RR

    Proc Natl Acad Sci USA 2004 May 18: 101(20) 7636-40 Epub 2004 May 10 PubMed PMID: 15136736 PubMed Central PMCID PMC419658

  • The effect of interspecific oocytes on demethylation of sperm DNA.

    Authors: Beaujean N, Taylor JE, McGarry M, Gardner JO, Wilmut I, Loi P, Ptak G, Galli C, Lazzari G, Bird A, Young LE, Meehan RR.

    Proc Natl Acad Sci U S A. 2004 May 18;101(20):7636-40.

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