Publications 2006-2009
Publications
Weigelt B, Geyer FC, Natrajan R, Lopez-Garcia MA, Ahmad AS, Savage K, Kreike B, Reis-Filho JS The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type
J Pathol 2009 Epub ahead of print. [original article]
Resetkova E, Reis-Filho JS, Jain RK, Mehta R, Thorat MA, Nakshatri H, Badve S Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment
Breast Cancer Res Treat 2009 Epub ahead of print. [original article]
Natrajan R, Weigelt B, Mackay A, Geyer FC, Grigoriadis A, Tan DS, Jones C, Lord CJ, Vatcheva R, Rodriguez-Pinilla SM, Palacios J, Ashworth A, Reis-Filho JS An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers
Breast Cancer Res Treat 2009 Epub ahead of print. [original article]
Bax DA, Gaspar N, Little SE, Marshall L, Perryman L, Regairaz M, Viana-Pereira M, Vuononvirta R, Sharp SY, Reis-Filho JS, Stávale JN, Al-Sarraj S, Reis RM, Vassal G, Pearson AD, Hargrave D, Ellison DW, Workman P, Jones C. EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines
Clin Cancer Res 2009 15:5753-61. [original article]
Weigelt B, Geyer FC, Horlings HM, Kreike B, Halfwerk H, Reis-Filho JS. Mucinous and neuroendocrine breast carcinomas are transcriptionally distinct from invasive ductal carcinomas of no special type
Mod Pathol 2009 22:1401-14. [original article]
Packer LM, East P, Reis-Filho JS, Marais R Identification of direct transcriptional targets of BRAF/MEK signalling in melanoma
Pigment Cell Melanoma Res 2009 22:785-98. [original article]
McCarthy A, Lord CJ, Savage K, Grigoriadis A, Smith DP, Weigelt B, Reis-Filho JS, Ashworth A Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation
J Pathol 2009 219:306-16. [original article]
Marchiò C, Lambros MB, Gugliotta P, Di CantognoLV, Botta C, Pasini B, Tan DSP, Mackay A, Fenwick K, Tamber N, Bussolati G, Ashworth A, Reis-Filho JS, Sapino A Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridisation and microarray-based CGH analysis
J Pathol 2009 219:16-24. [original article]
Martinho O, Longatto-Filho A, Lambros MB, Martins A, Pinheiro C, Silva A, Pardal F, Amorim J, Mackay A, Milanezi F, Tamber N, Fenwick K, Ashworth A, Reis-Filho JS, Lopes JM, Reis RM Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas
Br J Cancer 2009 101:973-82. [original article]
Westbury CB, Reis-Filho JS, Dexter T, Mahler-Araujo B, Fenwick K, Iravani M, Grigoriadis A, Parry S, Robertson D, Mackay A, Ashworth A, Yarnold JR, Isacke CM Genome-wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (cKit, CD117) and oestrogen receptor- (ER) in response to therapeutic radiation
J Pathol 2009 219:131-40. [original article]
Marchiò C, Iravani M, Natrajan R, Lambros MB, Geyer FC, Savage K, Parry S, Tamber N, Fenwick K, Mackay A, Schmitt FC, Bussolati G, Ellis I, Ashworth A, Sapino A, Reis-Filho JS Mixed micropapillary-ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components
J Pathol 2009 218:301-15. [original article]
Weigelt B, Kreike B, Reis-Filho JS Metaplastic breast carcinomas are basal-like breast cancers: a genomic profiling analysis
Breast Cancer Res Treat 2009 117:273-80. [original article]
Rocha RM, Nunes CB, Sanches FS, Rocha GF, Oliveira FN, Reis-Filho JS, Lambros MB, Gobbi H Rabbit antibodies for hormone receptors and HER2 evaluation in breast cancer
Rev Assoc Med Bras 2009 55:163-8. [original article]
Dhomen N*, Reis-Filho JS*, Da Rocha Dias S*, Hayward R, Savage K, Delmas V, Larue L, Pritchard C, Marais R Oncogenic BRAF induces melanocyte senescence and progression to melanoma in mice
Cancer Cell 2009 15:294-303. [original article] *: contributed equally to this study
Natrajan R, Lambros MB, Rodrigues Pinilla SM, Moreno-Bueno G, Tan DS, Marchio C, Vatcheva R, Rayter S, Mahler-Araujo B, Fulford LG, Hungermann D, Mackay A, Grigoriadis A, Fenwick K, Tamber N, Hardisson D, Tutt A, Palacios J, Lord C, Buerger H, Ashworth A, Reis Filho JS Tiling path genomic profiling of grade III invasive ductal breast cancers
Clin Cancer Res 2009 15: 2711-22. [original article]
Tan DSP, Lambros MBK, Rayter S, Natrajan R, Vatcheva R, Gao Q, Marchio C, GeyerF, Savage K, Parry S, FenwickK, Tamber N, Mackay A, DexterT, JamesonC, Mccluggage WG, Williams A, Graham A, Faratian D, El-Bahrawy M, Paige AJ, Gabra H, Gore ME, Zvelebil M, Lord CJ, Kaye SB, Ashworth A, Reis Filho JS PPM1D is a potential therapeutic target in ovarian clear cell carcinomas.
Clin Cancer Res 2009 15: 2269-2280. [original article]
Iorns E, Lord CJ, Grigoriadis A, McDonald S, Fenwick K, Mackay A, Mein CA, Natrajan R, Savage K, Tamber N, Reis-Filho JS, Turner NC, Ashworth A Integrated functional, gene expression and genomic analysis for the identification of cancer targets
PLoS ONE 2009 4:e5120. [original article]
Klingbeil P, Natrajan R, Everitt G, Vatcheva R, Marchio C, Palacios J, Buerger H, Reis-Filho JS, Isacke CM CD44 is overexpressed in basal-like breast cancers but is not a driver of 11p13 amplification
Breast Cancer Res Treat 2009 epub ahead of print. [orginal article]
Lancashire LJ, Powe DG, Reis-Filho JS, Rakha E, Lemetre C, Weigelt B, Abdel-Fatah TM, Green AR, Mukta R, Blamey R, Paish EC, Rees RC, Ellis IO, Ball GR. A validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks
Breast Cancer Res Treat 2009 epub ahed of print. [original article]
Rakha EA, Elsheikh S, Aleskandarany M, Habashy H, Green A, Powe D, El-Sayed M, Benhasouna A, Brunet JS, Akslen L, Evans A, Blamey R, Reis-Filho JS, Foulkes WD, Ellis IO Triple negative breast cancer: distinguishing between basal and non-basal subtypes
Clin Cancer Res 2009 15: 2302-10. [original article]
Vuononvirta R, Sebire N, Messahel B, Perusinghe N, Reis-Filho JS, Pritchard-Jones K, Vujanic G, Jones C Expression of HGF and its receptor Met in Wilms tumours and nephrogenic rests reflects their roles in kidney development
Clin Cancer Res 2009 15: 2723-30. [original article]
Jones RL, Salter J, A’Hern R, Nerurkar A, Parton M, Reis-Filho JS, Smith IE, Dowsett M Relationship between oestrogen receptor status and proliferation in predicting response and long-term outcome to neoadjuvant chemotherapy for breast cancer.
Breast Cancer Res Treat 2009 apub ahead of print. [original article]
Natrajan R, Lambros MB, Geyer F, Marchio C, tan DS, Vatcheva R, Shiu KK, Hungermann D, Rodrigues Pinilla SM, Palacios J, Ashworth A, Buerger H, Reis Filho JS Loss of 16q in high grade breast cancer is associated with oestrogen receptor status: Evidence for progression in tumours with a luminal phenotype?
Genes Chromosomes Cancer 2009 48: 351-65. [original article]
Mackay A, Tamber N, Fenwick K, Iravani M, Grigoriadis A, Dexter T, Lord C J, Reis-Filho JS, Ashworth A A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines
Breast Cancer Res Treat 2009 epub ahead of print. [original article]
Vuononvirta R, Sebire NJ, Dallosso AR, Reis-Filho JS, Williams RD, Mackay A, Fenwick K, Grigoriadis A, Ashworth A, Pritchard-Jones K, Brown KW, Vujanic GM, Jones C Perilobar nephrogenic rests are nonobligate molecular genetic precursor lesions of insulin-like growth factor-ii-associated wilms tumors
Clin Cancer Res 2008 14: 7635-7644. [original article]
Marchio C, Natrajan R, Shiu KK, Lambros MB, Rodriguez-Pinilla SM, Tan DS, Lord CJ, Hungermann D, Fenwick K, Tamber N, Mackay A, Palacios J, Sapino A, Buerger H, Ashworth A, Reis-Filho JS The genomic profile of HER2-amplified breast cancers: the influence of ER status
J Pathol 2008 216: 399-407. [original article]
Parry S, Savage K, Marchio C, Reis-Filho JS Nestin is expressed in basal-like and triple negative breast cancers
J Clin Pathol 2008 61: 1045-50 [original article]
Jones RL, Salter J, A'hern R, Nerurkar A, Parton M, Reis-Filho JS, Smith IE, Dowsett M The prognostic significance of Ki67 before and after neoadjuvant chemotherapy in breast cancer
Breast Cancer Res Treat 2008 Epub ahead of print. [original article]
Elsheikh SE, Green AR, Rakha EA, Samaka RM, Ammar AA, Powe D, Reis-Filho JS, Ellis IO Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype
Br J Cancer 2008 99:327-34. [original article]
Nunes CB, Rocha RM, Reis-Filho JS, Lambros MB, Rocha GF, Sanches FS, Oliveira FN, Gobbi H. Comparative analysis of six different antibodies against Her2 including the novel rabbit monoclonal antibody (SP3) and chromogenic in situ hybridisation in breast carcinomas.
J Clin Pathol 2008 61:934-8. [orginal article]
Reis-Filho JS, Drury S, Lambros MB, Marchio C, Johnson N, Natrajan R, Salter J, Levey P, Fletcher O, Peto J, Ashworth A, Dowsett M ESR1 gene amplification in breast cancer: a common phenomenon?
Nat Genet 2008 40: 809-10. [letter]
Marchiò C, Iravani M, Natrajan R, Lambros M, Savage K, Tamber N, Fenwick K, Mackay A, Senetta R, Di Palma S, Schmitt FC, Bussolati G, Ellis I, Ashworth A, Sapino A, Reis-Filho JS Genomic and immunophenotypical characterisation of pure micropapillary carcinomas of the breast
J Pathol 2008 215: 398-410. [original article]
Simpson PT*, Reis-Filho JS*, Lambros MBK, Jones C, Steele D, Mackay A, Iravani M, Fenwick K, Dexter T, Jones A, Reid L, Da Silva L, Shin SJ, Hardisson D, Ashworth A, Schmitt F, Palacios J, Lakhani SR Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas
J Pathol 2008 215:231-244 [original article] *: contributed equally to this study
Reis-Filho JS, Natrajan R, Vatcheva R, Lambros MB, Marchió C, Mahler-Araújo B, Paish C, Hodi Z, Eusebi V, Ellis IO Is acinic cell carcinoma a variant of secretory carcinoma? A FISH study using ETV6 'split apart' probes
Histopathology 2008 52: 840-6. [original article]
Arriola E, Marchio C, Tan DS, Drury SC, Lambros MB, Natrajan R, Rodriguez-Pinilla SM, Mackay A, Tamber N, Fenwick K, Jones C, Dowsett M, Ashworth A, Reis-Filho JS Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines
Lab Invest 2008 88: 491-503 [original article]
Robertson D, Savage K, Reis-Filho JS, Isacke CM Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue
BMC Cell Biol 2008 19: 13. [original article]
Abdel-Fatah TM, Powe DG, Hodi Z, Reis-Filho JS, Lee AH, Ellis IO Morphologic and Molecular Evolutionary Pathways of Low Nuclear Grade Invasive Breast Cancers and Their Putative Precursor Lesions: Further Evidence to Support the Concept of Low Nuclear Grade Breast Neoplasia Family
Am J Surg Pathol 2008 32: 513-23 [original article]
Edwards SL, Brough R, Lord CJ, Natrajan R, Vatcheva R, Levine DA, Boyd J, Reis-Filho JS, Ashworth A Resistance to therapy caused by intragenic deletions in the BRCA2 gene
Nature 2008 451:1111-5. [original article]
Mahler-Araujo B, Savage K, Parry S, Reis-Filho JS Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotype
J Clin Pathol 2008 61:615-20. [original article]
Thorat MA, Marchio C, Morimiya A, Savage K, Nakshatri H, Reis-Filho JS, Badve S FOXA1 expression in breast cancer is associated with Luminal subtype and good prognosis.
J Clin Pathol 2008 61: 327-32 [original article]
Savage K, Leung S, Todd SK, Brown LA, Jones RL, Robertson D, James M, Parry S, Rodrigues Pinilla SM, Huntsman D, Reis-Filho JS Distribution and significance of Caveolin 2 expression in normal breast and invasive breast cancer: an immunofluorescence and immunohistochemical analysis
Breast Cancer Res Treat 2008 110:245-56. [original article]
Elsheikh S, Green AR, Aleskandarany MA, Grainge M, Paish CE, Lambros MBK, Reis-Filho JS, Ellis IO CCND1 Amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome
Breast Cancer Res Treat 2008 109:325-35. [original article]
Natrajan R, Warren W, Messahel B, Reis-Filho J, Brundler MA, Dome J, Grundy P, Vujanic G, Pritchard-Jones K, Jones C Complex patterns of chromosome 9 alterations including the p16INK4A locus in Wilms tumours
J Clin Pathol 2008 61:95-102. [original article]
Esseghir S, Todd SK, Hunt T, Poulsom R, Plaza-Menacho I, Reis-Filho JS, Isacke CM A role for glial cell derived neurotrophic factor induced expression by inflammatory cytokines and RET/GFR alpha 1 receptor up-regulation in breast cancer.
Cancer Res 2007 67: 11732-41. [original article]
Tan DSP, Marchio C, Jones RL, Savage K, Smith IE, Dowsett M, Reis-Filho JS Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients
Breast Cancer Res Treat 2008 111:27-44. [original article]
Lee AHS, Paish EC, Marchio C, Sapino A, Schmitt FC, Ellis IO, Reis-Filho JS The expression of Wilms’ tumour-1 and Ca125 in invasive micropapillary carcinoma of the breast
Histopathology 2007 51: 824–828. [original article]
Arriola E, Rodriguez-Pinilla SM, Lambros MB, Jones RL, James M, Savage K, Smith IE, Dowsett M, Reis-Filho JS Topoisomerase II alpha amplification may predict benefit from adjuvant anthracyclines in HER2 positive early breast cancer
Breast Cancer Res Treat 2007 106: 181-9. [original article]
Jones C, Rodriguez-Pinilla M, Lambros M, Bax D, Messahel B, Vujanic GM, Reis-Filho JS, Pritchard-Jones K c-KIT overexpression, without gene amplification and mutation, in paediatric renal tumours
J Clin Pathol 2007 60:1226-31. [original article]
Wienke D, Davies GC, Johnson DA, Sturge J, Lambros MBK, Savage K, Elsheikh SE, Green AR, Ellis IO, Robertson D, Reis-Filho JS, Isacke CM The collagen receptor Endo180 (CD280) is expressed on basal-like breast tumor cells and promotes tumor growth in vivo
Cancer Res 2007 67: 10230-40. [original article]
Gomes AL, Reis-Filho JS, Lopes JM, Martinho O, Lambros MBK., Martins A, Schmitt F, Pardal F, Reis RM. Molecular alterations of KIT oncogene in gliomas
Cell Oncol 2007 29: 399-408. [original report]
Little SE, Bax DA, Rodriguez-Pinilla M, Natrajan R, Messahel B, Pritchard-Jones K, Vujanic GM, Reis-Filho JS, Jones C Multifaceted Dysregulation of the Epidermal Growth Factor Receptor Pathway in Clear Cell Sarcoma of the Kidney
Clin Cancer Res 2007 13:436-64. [original article]
Esseghir S, Kennedy A, Seedhar P, Nerurkar A, Poulsom R, Reis-Filho JS, Isacke CM Identification of NTN4, TRA1 and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins
Clin Cancer Res 2007 13:3164-73. [original article]
Svensson Månsson S, Reis-Filho J, Landberg G Transcriptional upregulation and unmethylation of the promoter region of p16 in invasive basal cell carcinoma cells and partial co-localisation with the G2 chain of laminin-332
J Pathol 2007 212:102-11. [original article]
Tischkowitz M, Xia X, Sabbaghian N, Reis-Filho JS, Hamel N, Li G, van Beers E, Li L, Khalil T, Quenneville L, Omeroglu A, Poll A, Lepage P, Wong N, Nederlof PM, Ashworth A, Tonin PN, Narod SA, Livingston DM, Foulkes WD Analysis of PALB2/FANCN–associated breast cancer families
Proc Natl Acad Sci U S A 2007 104:6788-93. [original article]
Elsheikh SE, Green AR, Lambros MBK, Turner NC, Grainge MJ, Powe D, Ellis IO, Reis-Filho JS FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis
Breast Cancer Res 2007 9: R23. [original article]
Turner NC, Reis-Filho JS, Russel AM, Springall RJ, Ryder K, Steele D, Savage K, Gillet CE, Schmitt FC, Tutt AN, Ashworth A. BRCA1 dysfunction in sporadic basal-like breast cancer
Oncogene 2007 26:2126-32. [original article]
Rodriguez-Pinilla SM, Sarrio D, Moreno-Bueno G, Rodriguez-Gil Y, Martinez MA, Hernandez L, Hardisson D, Reis-Filho JS, Palacios J Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer
Mod Pathol 2007 20:474-81. [original article]
Amary MF, Berisha F, Bernardi FD, Herbert A, James M, Reis-Filho JS, Fisher C, Nicholson AG, Tirabosco R, Diss TC, Flanagan AM Detection of SS18-SSX fusion transcripts in formalin-fixed paraffin-embedded neoplasms: analysis of conventional RT-PCR, qRT-PCR and dual color FISH as diagnostic tools for synovial sarcoma
Mod Pathol 2007 20:482-96. [original article]
Briassouli P, Chan F, Savage K, Reis-Filho JS, Linardopoulos S Aurora-A regulation of nuclear factor-kappaB signaling by phosphorylation of IkappaBalpha.
Cancer Res 2007 67: 1689-95. [original article]
McCarthy A, Savage K, Gabriel A, Naceur C, Reis-Filho JS, Ashworth A A mouse model of basal-like breast carcinoma with metaplastic elements
J Pathol 2007 211: 389-98. [original article]
Fulford LG, Reis-Filho JS, Ryder K, Jones C, Gillett CE, Hanby A, Easton DF, Lakhani SR Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival
Breast Cancer Res 2007 9:R4. [original article]
Savage K, Lambros MBK, Robertson D, Jones RL, Jones C, Mackay A, James M, Hornick JL, Pereira EM, Milanezi F, Fletcher CDM, Schmitt FC, Ashworth A, Reis-Filho JS Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphological, ultrastructural, immunohistochemical and in situ hybridisation analysis
Clin Cancer Res 2007 13:90-101. [original article]
Arriola E, Lambros MBK, Jones C, Dexter T, Mackay A, Tan DSP, Tamber N, Fenwick K, Ashworth A, Dowsett M, Reis-Filho JS Evaluation of Phi29-based whole genome amplification for microarray-based comparative genomic hybridisation
Lab Invest 2007 87:75-83. [original article]
Rodriguez-Pinilla SM, Jones RL, Lambros MBK, Arriola E, Savage K, James M, Pinder SE, Reis-Filho JS MYC amplification in breast cancer: a chromogenic in situ hybridisation study.
J Clin Pathol 2007 60:1017-23 [Epub ahead of print]. [original article]
Pierga JY, Reis-Filho JS, Cleator SJ, Dexter T, Mackay A, Simpson P, Fenwick K, Iravani M, Salter J, Hills M, Jones C, Ashworth A, Smith IE, Powles T, Dowsett M Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy
Br J Cancer 2007 96:341-51 [original article]
Abdel-Fatah TMA, Powe DG, Hodi Z, Lee AHS, Reis-Filho JS, Ellis IO High Frequency of coexistence of columnar cell lesions, lobular neoplasia and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma
Am J Surg Pathol 2007 31: 417-426. [original article]
Di Palma S, Lambros MBK, Savage K, Jones C, Mackay A, Dexter T, Iravani M, Fenwick K, Ashworth A, Reis-Filho JS Oncocytic change in pleomorphic adenoma: molecular evidence in support of an origin in neoplastic cells
J Clin Pathol 2007 60:492-9 [original article]
Reis-Filho JS, Simpson PT, Turner N, MB Lambros, Jones C, Mackay A, Grigoriadis A, Sarrio D, Savage K, Dexter T, Iravani M, Fenwick K, Weber B, Hardisson D, Schmitt FC, Palacios J, Lakhani SR, Ashworth A FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas
Clin Cancer Res 2006 12:6652-62. [original article]
Natrajan R, Little S, Sodha N, Reis-Filho JS, Mackay A, Fenwick K, Ashworth A, Perlman E, Dome J, Grundy P, Pritchard-Jones K, Jones C. Analysis by array CGH of genomic changes associated with the progression or relapse of Wilms' tumour
J Pathol 2006 13;211: 52-59 [original article]
Natrajan R, Reis-Filho JS, Little SE, Warren W, Messahel B, Brunder MA, Vujanic G, Pritchard-Jones K, Jones C Blastemal expression of IGF1R in Wilms tumours is driven by increased copy number and correlates with relapse
Cancer Res 2006 66: 11148-55. [original article]
Esseghir S, Reis-Filho JS, Kennedy A, James M, O'hare M, Jeffery R, Poulsom R, Isacke C. Identification of transmembrane proteins as potential prognostic markers and therapeutic targets in breast cancer by a screen for signal sequence encoding transcripts
J Pathol 2006 210: 420-430. [original article]
Grigoriadis A, Mackay A, Reis-Filho JS, Steele D, Iseli C, Stevenson BJ, Jongeneel CV, Valgeirsson H, Fenwick K, Iravani M, Leao M, Simpson AJ, Strausberg RL, Jat PS, Ashworth A, Neville AM, O'hare MJ Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data
Breast Cancer Res 2006 8:R56. [original article]
Natrajan R, Little SE, Reis-Filho JS, Hing L, Messahel B, Grundy PE, Schneider T, Vujanic G, Pritchard-Jones K, Jones C Amplification and overexpression of CACNA1E correlates with relapse in favourable histology wilms tumours
Clin Cancer Res 2006 12:7284-93. [original article]
Natrajan R, Williams RD, Hing SN, Mackay A, Reis-Filho JS, Fenwick K, Iravani M, Valgeirsson H, Grigoriadis A, Langford CF, Dovey O, Gregory SG, Weber BL, Ashworth A, Grundy PE, Pritchard-Jones K, Jones C Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse
J Pathol 2006 210:49-58 [original article]
Reis-Filho JS, Savage K, Lambros M, James M, Steele D, Jones RL, Dowsett M Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis
Mod Pathol 2006 19: 999-1009. [original article]
Reis-Filho JS, Pinheiro C, Lambros MBK, Milanezi F, Carvalho S, Savage K, Simpson PT, Jones C, Swift S, Mackay A, Reis RM, Hornick JL, Pereira EM, Baltazar F, Fletcher CDM, Ashworth A, Lakhani SR, Schmitt FC EGFR amplification and lack of activating mutations in metaplastic breast carcinomas
J Pathol 2006 209: 445-453. [original article]
Reis-Filho JS, Milanezi F, Steele D, Savage K, Simpson PT, Pereira EM, Nesland JM, Lakhani SR, Schmitt FC Metaplastic breast carcinomas are basal-like tumours
Histopathology 2006 49: 10-21. [original article]
Fulford LG, Easton DF, Reis-Filho JS, Sofronis A, Gillett CE, Lakhani SR, Hanby A. Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast
Histopathology 2006 49: 22-34. [original article]
Banerjee S, Reis-Filho JS, Ashley S, Steele D, Ashowrth A, Lakhani SR, Smith IE Basal-Like Breast Carcinomas: clinical outcome and response to chemotherapy
J Clin Pathol 2006; 59: 729-35. [original article]
Lambros MBK, Simpson PT, Jones C, Natrajan R, Westbury C, Steele D, Savage K, Mackay A, Schmitt FC, Ashworth A, Reis-Filho JS Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridisation
Lab Invest 2006 86:398-408. [original article]
Reis-Filho JS, Steele D, Di Palma S, Jones RL, Savage K, James M, Milanezi F, Schmitt FC, Ashworth A Distribution and significance of nerve growth factor receptor (NGFR/p75NTR) in normal, benign and malignant breast tissue
Mod Pathol 2006 19: 307-19. [original article]
Reis Filho JS Next Generation Sequencing
Breast Cancer Res 2010 in press. [short communication]
Weigelt B, Baehner FL, Reis-Filho JS The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade
J Pathol 2009 DOI: 10.1002/path.2648. [review]
Weigelt B, Reis-Filho JS Histological and molecular types of breast cancer: is there a unifying taxonomy?
Nat Rev Clin Oncol 2009 DOI:10.1038/nrclinonc.2009.1166. [review]
Geyer FC, Lopez-Garcia MA, Lambros MB, Reis-Filho JS Genetic Characterisation of Breast Cancer and Implications for Clinical Management
J Cell Mol Med 2009 Epub ahead of print. [review]
Rakha E Reis-Filho JS Basal-like breast carcinoma: from expression profiling to routine practice
Archives of Pathology and Laboratory Medicine 2009 133:860-8. [review]
Geyer F, Reis-Filho JS Microarray-based prognostic signatures: are we there yet?
Int J Surg Pathol 2009; 17:285-302. [review]
Geyer FC, Decker T, Reis-Filho JS Genome-wide expression profiling as a clinical tool: are we there yet?
Pathologe 2009 30:141-6. [review]
Geyer F, Marchio C, Reis-Filho JS The role of molecular analysis in breast cancer
Pathology 2009 41: 77-88. [review]
Tan DSP, Lambros MB, Marchio C, Reis-Filho JS ESR1 gene amplification in endometrial cancer: hope or hyperbole?
J Pathol 2008 216: 271-4. [invited commentary]
Reis-Filho JS, Lakhani SR Special types of breast cancer: Why bother?
J Pathol 2008; 216: 394-8 [invited commentary]
Shiu KK, Tan DS, Reis-Filho JS Development of therapeutic approaches to 'triple negative' phenotype breast cancer
Expert Opin Ther Targets 2008; 12:1123-37. [review]
Tan DS, Marchio C, Reis Filho JS Hereditary breast cancer: From molecular pathology to tailored therapies
J Clin Pathol 2008 61: 1073-82. [review]
Rakha EA, Ellis IO, Reis-Filho JS Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas).
Mod Pathol 2008 21:1060-1. [letter to the editor]
Tan DS, Reis-Filho JS Comparative genomic hybridisation arrays: high-throughput tools to determine targeted therapy in breast cancer
Pathobiology 2008 75: 63-74. [review]
Rakha EA, Reis-Filho JS, Ellis IO Impact of Basal-like breast carcinoma determination for a more specific therapy
Pathobiology 2008 75: 95-103. [review]
Rakha EA, Reis-Filho JS, Ellis IO Basal-like breast cancer: a critical review
J Clin Oncol 2008 26: 2568-81. [review]
Rakha EA, El-Sayed ME, Reis-Filho J, Ellis IO Patho-biological aspects of basal-like breast cancer
Breast Cancer Res Treat 2008 Epub ahead of print. [review]
Smalley MJ, Reis-Filho JS, Ashworth A BRCA1 and stem cells: tumour typecasting
Nat Cell Biol 2008 10: 377-9. [editorial]
Rakha EA, Ellis IO, Reis-Filho JS Are Triple-Negative and Basal-Like Breast Cancer Synonymous?
Clin Cancer Res 2008 14: 618 [letter to the editor]
Reis-Filho JS, Tutt AN Triple negative breast cancer: a critical review
Histopathology 2008 52: 108–118. [review]
Rakha EA, El-Sayed ME, Reis-Filho JS, Ellis IO. Expression profiling technology: its contribution to our understanding of breast cancer
Histopathology 2008 52: 67–81 [review]
Reis-Filho JS, Pinder SE Non operative breast pathology: lobular neoplasia
J Clin Pathol 2007 60;1321-1327. [review]
Pinder SE, Reis-Filho JS Non operative breast pathology: columnar cell lesions
J Clin Pathol 2007 60;1307-1312. [review]
Pinder SE, Reis-Filho JS Non-operative breast pathology
J Clin Pathol 2007 60: 1297-1299. [editorial]
Rakha EA, Tan DS, Foulkes WD, Ellis IO, Tutt A, Nielsen TO, Reis-Filho JS Are triple negative tumours and basal-like breast cancer synonymous?
Breast Cancer Res. 2007 Nov 13;9(6):R80. [Letter to the Editor]
Lambros MB, Natrajan R, Reis-Filho JS Fluorescent and chromogenic in situ hybridisation in breast cancer
Hum Pathol 2007 38:1105-22. [review]
Tan DSP, Lambros MBK, Natrajan R, Reis-Filho JS Getting it right: designing microarray (and not ‘microawry’) comparative genomic hybridisation studies for cancer research.
Lab Invest 2007 87:737-54. [review]
Pinder SE, Provenzano E, Reis-Filho JS Lobular in situ neoplasia and columnar cell lesions: diagnosis in breast core biopsies and implications for management
Pathology 2007 39: 208-16. [review]
Turner NC, Reis-Filho JS Basal-like breast cancer and BRCA1 phenotype
Oncogene 2006 25: 5846-53 [review]
Reis-Filho JS, Westbury C, Pierga JY The impact of expression profiling on prognostic and predictive testing in breast cancer
J Clin Pathol 2006 59: 225-31. [review]
Geyer FC, Kushner YB, Lambros MB, Natrajan R, Mackay A, Tamber N, Fenwick K, Purnell D, Ashworth A, Walker RA, Reis-Filho JS Microglandular Adenosis or Microglandular Adenoma? A Molecular Genetic Analysis of a Case Associated with Atypia and Invasive Carcinoma
Histopathology 2009 in press. [case report]
Lambros MB, Tan DS, Jones RL, Vatcheva R, Savage K, Tamber N, Fenwick K, Mackay A, Ashworth A, Reis-Filho JS Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication
J Clin Pathol 2009 62: 604-12. [case report]
