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Identification of the molecular drivers of special types of breast cancer
Determining the genotypic-phenotypic correlations in breast cancer and the main molecular drivers of each special type of breast cancer.
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Classic and pleomorphic lobular carcinoma
Defining the molecular genetic characteristics of classic and pleomorphic lobular carcinomas and identifying novel therapeutic targets for these tumours.
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Basal-like carcinomas
Analysing the biological and clinical impacts of BRCA1 inactivation in basal-like carcinomas.
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HER2 positive breast cancer
Identifying novel predictive markers and therapeutic targets for HER2-positive breast cancers.
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Unravelling intra-tumour genetic heterogeneity of breast cancer
Characterising the genetic intra-tumour heterogeneity of breast cancers and its significance for resistance to tailored therapies.
