Publications

Zvelebil MJ & Baum JO Understanding Bioinformatics (book)

(2007) Garland Publishing Inc,US; ISBN 0815340249.

Miled N, Yan Y, Hon WC, Perisic O, Zvelebil M, Inbar Y, Schneidman-Duhovny. Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit.

Science (2007) 13, 239-242.

Gharbi SI, Zvelebil MJ, Shuttleworth SJ, Hancox T, Saghir N, Timms JF, Waterfield MD. Exploring the specificity of the PI3K family inhibitor LY294002.

Biochem J. (2007) 404, 15-21.

Seoighe C, Ketwaroo F, Pillay V, Scheffler K, Wood N, Duffet R, Zvelebil M, Martinson N, McIntyre J, Morris L and Hide W. A model of directional selection applied to the evolution of drug resistance in HIV-1

Molecular Biology and Evolution (2007) 24, 1025-1031.

Maloney A, Clarke PA, Naaby-Hansen S, Stein R, Koopman J, Akpan A, Yang A, Zvelebil M, Cramer R, Stimson L, Aherne W, Banerji U, Judson I, Sharp S, Powers M, deBilly E, Salmons J, Walton M, Burlingame A, Waterfield M and Workman P. Gene and protein expression profiling of human ovarian cancer cells treated with the HSP90 inhibitor 17-allylamino-17-demethoxy geldanamycin (17AAG)

Cancer Research (2007) 67, 3239-53.

Bergamaschi D, Samuels Y, Sullivan A, Zvelebil M, Breyssens H, Bisso A, Del Sal G, Syed N, Smith P, Gasco M, Crook T & Lu X. iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72–polymorphic p53.

Nature Genetics (2006) 38: 1133-1141

Ng A. Bursteinas B. Gao Q. Mollison E. and Zvelebil M. Resources for integrative systems biology: From data through databases to networks and dynamic system models.

Briefings in Bioinformatics (2006) 7, 318-330.

Sims D, Bursteinas B, Gao Q, Zvelebil M, Baum B. FLIGHT: database and tools for the integration and cross-correlation of large-scale RNAi phenotypic datasets.

N.A.R (2006) 34, D479-D483.

Ng A, Bursteinas B, Gao Q, Mollison E, Zvelebil M. pSTIING: a ‘systems’ approach towards integrating signalling pathways, interaction and transcriptional regulatory networks in inflammation and cancer.

N.A.R (2006)34, D527-D534.

Williams, J.G. and Zvelebil, M. SH2 domains in plants.

Trends in Plant Science (2004) 9,161-163.

Zhukovskaya, N.V., Fukuzawa, M., Tsujioka, M., Jermyn, K.A., Kawata, T., Zvelebil, M. and Williams, J.G. Dd-STATb, a Dictyostelium STAT protein with a highly aberrant SH2 domain, functions as a regulator of gene expression during growth and early development.

Development (2004) 131, 447-458.

Nagano K, Masters JR, Akpan A, Yang A, Corless S, Wood C, Hastie C, Zvelebil M, Cramer R, Naaby-Hansen S Differential protein synthesis and expression levels in normal and neoplastic human prostate cells and their regulation by type I and II interferons.

Oncogene (2004) 23, 1693-703.