-
IAPs – The last line of defence against caspase-mediated damage
Investigating the molecular mechanism through which IAPs block caspases
-
Setting up the anti-apoptotoic threshold
Elucidating how the protein levels of IAPs is regulated.
-
IAP antagonists – Overcoming the anti-apoptotic roadblock
Investigating IAP-binding proteins to identify novel IAP-regulatory proteins.
-
Ubiquitylation in apoptosis
Studying the mechanism of IAP-mediated signalling.
-
Caspase-independent function of IAPs
Linking microbial infections to chronic inflammation and cancer.
